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Image Search Results
Journal: Neurochemical Research
Article Title: Hydrogen Sulphide-Based Therapeutics for Neurological Conditions: Perspectives and Challenges
doi: 10.1007/s11064-023-03887-y
Figure Lengend Snippet: Protective roles of H 2 S donors in neurological disease models
Article Snippet: Stroke ,
Techniques: Injection, Transformation Assay, Transgenic Assay, Mutagenesis, Isolation, Cell Culture, Saline
Journal: Journal of Neuroinflammation
Article Title: CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation
doi: 10.1186/s12974-020-1727-6
Figure Lengend Snippet: Loss of CLEC14A exacerbated cerebral injury with VEGFR2 activation in MCAO stroke model. a , c Images of whole brains and comparison of Evans blue dye (EB) leakage in brains (P8 and adult) after EB injection (intraperitoneal route) in WT and CLEC14A KO mice ( n = 6, each group). b , d The quantitative analysis of Evans blue (EB) dye extravasation using spectrophotometer, 24 h after intraperitoneal injection of EB dye. e TTC staining of brain slices in the sham, WT, and CLEC14A KO groups 24-h post ischemia-reperfusion. Severe infarction was present in the CLEC14A KO group. Scale bar = 1 mm. f Percentage of infarct volume in the WT and CLEC14A KO groups 24 h after ischemia-reperfusion. g Neurological scores of WT and CLEC14A KO mice were evaluated. h VEGFR2, pVEGFR2 protein expression in ipsilateral brain lysate after ischemia-reperfusion injury. i , j Quantification data of relative pVEGFR2 and VEGFR2 protein expression. n = 6 per group; * P < 0.05, ** P < 0.01, *** P < 0.001. The results are mean values and the error bars represent the mean ± SD
Article Snippet: A 6–0 fine
Techniques: Activation Assay, Comparison, Injection, Spectrophotometry, Staining, Expressing